{"id":4270,"date":"2024-09-06T15:14:26","date_gmt":"2024-09-06T19:14:26","guid":{"rendered":"https:\/\/shepherd.org\/?page_id=4270"},"modified":"2025-03-13T10:27:30","modified_gmt":"2025-03-13T14:27:30","slug":"multiple-sclerosis","status":"publish","type":"page","link":"https:\/\/shepherd.org\/research\/research-areas\/multiple-sclerosis\/","title":{"rendered":"Multiple Sclerosis Research"},"content":{"rendered":"<div class=\"hero-container hero-container--with-sidenav hero-container__hero-small_image\">\n  <div class=\"hero hero-small_image\">\n    <div class=\"hero__title_container\">\n      <h1 class=\"hero__title\">\n                  \n              <\/h1>\n              <nav class=\"breadcrumbs\" aria-label=\"Breadcrumb\">\n\t<ol class=\"breadcrumbs__list\">\n\t\t\t\t\t<li><a href=\"https:\/\/shepherd.org\">Home<\/a><\/li><li><a href=\"\">Pages<\/a><\/li>\n\t\t\t<\/ol>\n<\/nav>      \n          <\/div>\n          <div class=\"hero__image-container\">\n        <img decoding=\"async\" src=\"https:\/\/shepherd.org\/wp-content\/uploads\/2024\/09\/research-ms-0006.jpg?ver=1732750518\" alt=\"Two healthcare professionals examine the arm of an older man sitting in a chair in a medical office. The man wears a red sweater and a winter hat.\"\/>\n      <\/div>\n      <\/div>\n      <nav class=\"sidenav\" aria-label=\"Sidenav\">\n\t<div class=\"sidenav__list\" id=\"sidenav-list\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t<ul>\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t<a href=\"\/\">Home<\/a>\n\t\t\t\t\t<\/li>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/admissions\/\"   target=\"_self\" >Admissions<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t  \n  \t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/outcomes\/\"   target=\"_self\" >Outcomes<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t  \n  \t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/research\/\"   target=\"_self\" >Research<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t  \n  \t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/education\/\"   target=\"_self\" >Education<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t  \n  \t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/about\/\"   target=\"_self\" >About Us<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t  \n  \t\t\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<\/ul>\n\t\t\t<\/div>\n<\/nav>\n  <\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--text-html\">\n\t<div class=\"idf-block text-content\">\n\t\t<h2>Participate in multiple sclerosis clinical, rehabilitation, and wellness trials<\/h2>\n<p>At Shepherd Center, our multiple sclerosis (MS) research program focuses on improving clinical outcomes and enhancing the quality of life for individuals with MS. We conduct a range of clinical trials and rehabilitation and wellness intervention studies. Our commitment to scientifically sound methods and participant safety helps advance the field of rehabilitation medicine.<\/p>\n<h2>About our multiple sclerosis research program<\/h2>\n<p>Since 2012, our research has supported the MS clinical program through the Eula C. and Andrew C. Carlos MS Rehabilitation and Wellness Program. Our mission is to improve function, health, wellness, and quality of life for people with MS, especially those facing mobility challenges or limited access to rehabilitation.<\/p>\n<p>Our research explores the impact of both physical and cognitive rehabilitation interventions. We also study how these interventions affect vocational outcomes and overall quality of life. By disseminating our findings to patients, healthcare providers, caregivers, and payers, we aim to optimize care for those living with MS.<\/p>\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--buttons idf-block\">\n\t<div class=\"is-layout-flex wp-block-buttons\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"wp-block-button\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"wp-fancy__link\" href=\"https:\/\/shepherd.org\/treatment\/services-clinics\/ms-institute\/treatment\/wellness\/\" >\n\t\t\t\t\t\t\tMore About Our MS Wellness Program\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--text-html\">\n\t<div class=\"idf-block text-content\">\n\t\t<h2>Current MS trials seeking participants<\/h2>\n<p>Do you qualify to be an MS trial research participant? See the list below to learn more about the current multiple sclerosis clinical trials and studies at Shepherd Center.<\/p>\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--accordion idf-block accordion\" id=\"accordionFlush8807\">\n            <div class=\"accordion__accordion\">\n      <h3 class=\"accordion__title\" id=\"flush-heading_8807_1\">\n        <button class=\"accordion__trigger\" type=\"button\" data-bs-toggle=\"collapse\" data-bs-target=\"#flush-collapse_8807_1\" aria-expanded=\"false\" aria-controls=\"flush-collapse_8807_1\">\n          The Calliper study: multicenter, randomized, double-blind, placebo-controlled study to evaluate efficacy, safety, and tolerability of IMU-838 in patients with progressive multiple sclerosis<span class=\"sp-before-icon\"><\/span>\n        <\/button>\n      <\/h3>\n      <\/h2>\n      <div role=\"region\" id=\"flush-collapse_8807_1\" class=\"accordion__content\" aria-labelledby=\"flush-heading_8807_1\" data-bs-parent=\"#accordionFlush8807\">\n        <div class=\"accordion__content-wrap text-content\"><h4>Purpose of trial<\/h4>\n<p>This study is being done for patients who have a diagnosis of Primary or Secondary Progressive Multiple Sclerosis. The purpose of this study is to assess the effects of an investigational product called IMU-838, a tablet containing vidofludimus calcium, on disease activity and to assess safety.<\/p>\n<h4>Participation eligibility<\/h4>\n<ul>\n<li>Be between the ages of 18 and 65.<\/li>\n<li>Be stable with no relapses for the past 24 months.<\/li>\n<li>Have a diagnosis of primary or secondary progressive multiple sclerosis.<\/li>\n<\/ul>\n<h4>More information<\/h4>\n<p>To learn more about this clinical trial, contact Ashley Howard, RN, BSN, at <a href=\"tel:404-367-1279\">404-367-1279<\/a> or email <a href=\"mailto:ashley.howard@shepherd.org\">ashley.howard@shepherd.org<\/a>.<\/p>\n<\/div>\n                                  <\/div>\n    <\/div>\n          <div class=\"accordion__accordion\">\n      <h3 class=\"accordion__title\" id=\"flush-heading_8807_2\">\n        <button class=\"accordion__trigger\" type=\"button\" data-bs-toggle=\"collapse\" data-bs-target=\"#flush-collapse_8807_2\" aria-expanded=\"false\" aria-controls=\"flush-collapse_8807_2\">\n          STEP for MS: a study to compare the impacts of an exercise program for people with MS when delivered at home compared to in a gym facility (738)<span class=\"sp-before-icon\"><\/span>\n        <\/button>\n      <\/h3>\n      <\/h2>\n      <div role=\"region\" id=\"flush-collapse_8807_2\" class=\"accordion__content\" aria-labelledby=\"flush-heading_8807_2\" data-bs-parent=\"#accordionFlush8807\">\n        <div class=\"accordion__content-wrap text-content\"><h4>Purpose of this trial<\/h4>\n<p>The purpose of this study is to determine whether an evidence-based exercise program delivered virtually by telephone and computer (\u201ctelerehab\u201d) produces the same benefits for improving walking and mobility, participation, and quality of life in people with multiple sclerosis when compared to delivery of the program in an exercise facility.<\/p>\n<p><strong>Recruitment for this study is now closed.<\/strong><\/p>\n<h4>More information<\/h4>\n<p>To learn more about this clinical trial, contact Erica Sutton at <a href=\"tel:404-367-1305\">404-367-1305<\/a> or email <a href=\"mailto:erica.sutton@shepherd.org\">erica.sutton@shepherd.org<\/a>.<\/p>\n<\/div>\n                                  <\/div>\n    <\/div>\n  <\/div>\n\n\n\t<div class=\"paragraph-widget paragraph-widget--feature-set idf-block\">\n\t\t<div class=\"feature\">\n\t\t\t\t\t\t\t<div class=\"feature__media\">\n\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/shepherd.org\/wp-content\/uploads\/2024\/09\/ms-outpatient-ms-institute-0104.jpg?ver=1732589539\" alt=\"A healthcare professional in light blue scrubs and purple gloves administers an IV to an older woman sitting in a chair. The woman, wearing glasses and a T-shirt with an Alaska design, smiles and looks at the healthcare professional.\" loading=\"lazy\">\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"feature__content\">\n\t\t\t\t<h3>Cutting-edge MS clinical trials<\/h3>\n\t\t\t\t\t\t\t\t\t<div class=\"feature__content-body text-content\"><p>Our Multiple Sclerosis Institute leads clinical trials exploring innovative therapies, including investigational medications, new cell therapies, and advanced medical devices. Lead by Ismari Clesson, our clinical research team oversees 12 ongoing trials, ensuring they meet the highest standards of scientific rigor and participant welfare.<\/p>\n<\/div>\n\t\t\t\t\t\t\t\t<ul>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/research\/clinical-trials\/\">More on Clinical Trials<\/a>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--text-html\">\n\t<div class=\"idf-block text-content\">\n\t\t<h2>Our MS research team<\/h2>\n<p>Shepherd Center\u2019s unique multiple sclerosis research program integrates clinical and research endeavors. This team, led by Dr. Deborah Backus, consists of physical and occupational therapists, speech therapists, exercise specialists, physicians and collaborators from a variety of fields and institutions. This integrated team endeavors to answer meaningful questions and translate findings into clinical practice.<\/p>\n<ul>\n<li>Deborah Backus, PT, Ph.D., FACRM, Vice President of Research and Innovation<\/li>\n<li>Brad Willingham, Ph.D., Director of MS Research<\/li>\n<li>Erica Sutton, Research Coordinator<\/li>\n<li>Julie Stowell, PT, D.P.T., Multiple Sclerosis Research Fellow<\/li>\n<\/ul>\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--text-html\">\n\t<div class=\"idf-block text-content\">\n\t\t<h2>MS clinical program team<\/h2>\n<p>At Shepherd Center, our interdisciplinary team of MS specialists, including neurologists, nurse practitioners, therapists, and more, provides comprehensive care. With access to specialized clinics and services, we ensure personalized treatment within a supportive and family-like environment.<\/p>\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--buttons idf-block\">\n\t<div class=\"is-layout-flex wp-block-buttons\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"wp-block-button\">\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"wp-fancy__link\" href=\"https:\/\/shepherd.org\/treatment\/services-clinics\/ms-institute\/care-team\/\" >\n\t\t\t\t\t\t\tMS Care Team\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--text-html\">\n\t<div class=\"idf-block text-content\">\n\t\t<h2>MS research team of collaborators, past and present<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.iconquerms.org\/step-ms-whos-involved\" target=\"_blank\" rel=\"noopener\">STEP for MS trial investigators<\/a><\/li>\n<li>Kevin McCully, Ph.D., University of Georgia, Augusta, Georgia, USA<\/li>\n<li>Laura Rice, Ph.D., MPT, ATP, University of Urbana-Champaign, Illinois, USA<\/li>\n<li>Jacob Sosnoff, Ph.D., Associate Dean, Research, School of Health Professions,<\/li>\n<li>Kansas University Medical Center<\/li>\n<li><a href=\"https:\/\/www.cando-ms.org\/\" target=\"_blank\" rel=\"noopener\">Can Do MS<\/a><\/li>\n<li><a href=\"https:\/\/www.iconquerms.org\/\" target=\"_blank\" rel=\"noopener\">iConquerMS<\/a><\/li>\n<li>Abiodun Akinwuntan, Ph.D., MPH, and Hannes Devos, Ph.D., Georgia Regents University, Georgia, USA<\/li>\n<li>Ilse Baert, Ph.D., and Peter Feys, Ph.D., Universiteit Hasselt, Biomedical Research Institute, Belgium<\/li>\n<li>James Krause, Ph.D., Medical University of South Carolina, South Carolina, USA<\/li>\n<\/ul>\n\n\t<\/div>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--news-feed\">\n\t<section aria-label=\"News Feed\" class=\"idf-block news-feed\">\n\t\t<div class=\"container\">\n\t\t\t<h2>From the Newsroom<\/h2>\n\t\t\t<div class=\"news-feed__wrap\">\n\t\t\t\t<ul>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t<article class=\"news-story\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"news-story__media\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/shepherd.org\/wp-content\/uploads\/2024\/09\/ms-outpatient-ms-institute-0100.jpg\" alt=\"PCORI-funded exercise study\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"news-story__content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"news-story__title\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/news.shepherd.org\/patient-centered-outcomes-research-institute-awards-57-million-in-research-funding--for-study-of-exercise-delivery-and-effects-in-people-with-multiple-sclerosis\/\" class=\"news-story-link\">PCORI-funded exercise study<\/a>\n\t\t\t\t\t\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"news-story__body\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"news-story__subtitle\">Shepherd Center leads a $5.7M PCORI study comparing traditional and telerehab for people with MS.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t<article class=\"news-story\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"news-story__media\">\n\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/shepherd.org\/wp-content\/uploads\/2024\/09\/research-ms-sensoria-socks-0003.jpg\" alt=\"Smart socks revolutionize MS rehab with real-time mobility tracking\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"news-story__content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"news-story__title\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/news.shepherd.org\/smart-socks-innovation-to-expand-accessibility-and-precision-of-rehabilitation-for-people-with-multiple-sclerosis\/\" class=\"news-story-link\">Smart socks revolutionize MS rehab with real-time mobility tracking<\/a>\n\t\t\t\t\t\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"news-story__body\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"news-story__subtitle\">Smart Socks expand rehab accessibility for people with MS by tracking walking patterns in daily life.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/section>\n<\/div>\n\n\n<div class=\"paragraph-widget paragraph-widget--link-block idf-block\">\n\t<div class=\"link-block\">\n\t\t\t\t\t<h2 class=\"link-block__label\">Continue Exploring<\/h2>\n\t\t\t\t<ul>\n\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/outcomes\/patient-outcomes\/\" >\n\t\t\t\t\t\tPatient Outcomes\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/research\/model-system-care\/\" >\n\t\t\t\t\t\tModel Systems of Care\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li>\n\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/shepherd.org\/research\/clinical-trials\/\" >\n\t\t\t\t\t\tClinical Trials\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Join MS clinical, rehab, and wellness trials at Shepherd Center to improve outcomes and quality of life.<\/p>\n","protected":false},"author":17,"featured_media":0,"parent":2922,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"_tec_requires_first_save":true,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","footnotes":""},"categories":[],"class_list":["post-4270","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.1 (Yoast SEO v25.5) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Multiple Sclerosis Research | Shepherd Center<\/title>\n<meta name=\"description\" content=\"Participate in MS clinical, rehab, and wellness trials at Shepherd Center, focusing on improving outcomes and quality of life for people with MS.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/shepherd.org\/research\/research-areas\/multiple-sclerosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multiple Sclerosis Research\" \/>\n<meta property=\"og:description\" content=\"Participate in MS clinical, rehab, and wellness trials at Shepherd Center, focusing on improving outcomes and quality of life for people with MS.\" \/>\n<meta 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